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Insulin resistance makes it harder for your body to utilize glucose (blood sugar) as a source of energy, leading to weight gain and increasing the risk of diabetes

doi: 10.1016/j.ejphar.2016.11.009

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FIGURE 9 5.3.5 ROS promotes UPS-mediated acceleration of protein degradation The ubiquitin-proteasome system (UPS) is the primary protein degradation machinery in eukaryotic cells, responsible for removing misfolded, damaged, or excess proteins to maintain proteostasis and regulate key cellular processes including cell cycle and immune signaling (Peris-Moreno et al., 2021)